Articles
For Rat Catheters, I’ll Have The CBAS® (Not The Fish)
Posted on Feb 18, 2012 by SolomonScientific
Infusion of test articles via a rat catheter in the jugular or femoral vein is a central procedure in drug safety testing. The most common premature endpoint of intravenous infusion models in rodents is catheter occlusion. The most proven material-based solution to this problem is use of the CBAS® (Carmeda BioActive Surface from Gore Medical) coating on a polyurethane substrate.
Back Off The Tethered Infusion Pump! Preventing Dosing Errors In Animal Studies
Posted on Feb 01, 2012 by SolomonScientific
Complications from an occlusion in a tethered infusion pump model include either an inadvertent bolus after resolving the occlusion or a dose under-reporting error. Modern syringe driver devices sold for human use all have a “back off” feature (also called an “anti-bolus”). When the occlusion alarm is activated and pumping stops, the back off feature reverses the driver direction until the pressure is reduced to a normal level.
Animal Infusion Pumps And Catheters For IV & CSF. How Low Can You Go?
Posted on Jan 22, 2012 by SolomonScientific
There are many applications, including CSF studies, for animal infusion pumps and catheter devices which administer low fluid volumes at low flow rates. Laboratory animal CSF infusion, for one, invariably requires low volumes of test article delivered at slow rates.
The Not-So-Mythical Winged Horse—Pegasus Lab Animal Infusion Pump
Posted on Jan 16, 2012 by SolomonScientific
It’s not so mythical any longer. An integration of the Pegasus® pump (Venner Medical GmbH) and the Orchesta® wireless automation system has yielded the most advanced research animal IV pump system—The Pegasus Lab Animal Infusion Pump System for use in dogs and nonhuman primates (monkeys).
It’s The Plumber. I’ve Come To Fix The Dog Infusion Catheter.
Posted on Jan 08, 2012 by SolomonScientific
The plumber has a few options to clear the pipes when a line implanted in the vein of a dog becomes occluded. These options comprise repositioning the animal, use of fibrinolytics, and waiting for another time or day. The plumber also has preventive tools in his bag to reduce the risk of animal catheter occlusion.
